Product: NH3-KLGADTDGEQDQHMTYGGQ-COOH
ABO, Blood Group A Antigen Antibody (33C13) [Alexa Fluor® 700] Summary
| Immunogen |
Mucin isolated from an ovarian cyst fluid
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| Localization |
Cell Surface
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| Specificity |
This MAb preferably reacts with determinants of chain A and H type 3(Gal1-3GalNAc-R) and 4 (Gal1-3GalNAc-R), but not with type 1 and 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This MAb is applicable for tissue staining in tumor patients with blood groups A and AB. It shows a highly heterogeneous reactivity in human colon tumor tissue and adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
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| Isotype |
IgG1 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
ABO
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| Purity |
Protein A or G purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Optimal dilution of this antibody shomld be experimentally determined.
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Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
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| Buffer |
50mM Sodium Borate
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| Preservative |
0.05% Sodium Azide
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| Purity |
Protein A or G purified
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Notes
This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
Alternate Names for ABO, Blood Group A Antigen Antibody (33C13) [Alexa Fluor® 700]
- A transferase
- A3GALNT
- A3GALT1
- ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase)
- ABO glycosyltransferase
- B transferase
- B(A) alpha-1,3-galactosyltransferase
- EC 2.4.1.37
- EC 2.4.1.40
- Fucosylglycoprotein 3-alpha-galactosyltransferase
- Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase
- Glycoprotein-fucosylgalactoside alpha-galactosyltransferase
- Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase
- GTB
- Histo-blood group A transferase
- histo-blood group A2 transferase
- histo-blood group ABO system transferase
- Histo-blood group B transferase
- NAGAT