AMPK alpha 1 Antibody (1G4) Summary
| Immunogen |
PRKAA1 (AAH12622 451 a.a. – 550 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
|
| Specificity |
PRKAA1 – protein kinase, AMP-activated, alpha 1 catalytic subunit
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
PRKAA1
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for AMPK alpha 1 Antibody (1G4)
- AMP -activate kinase alpha 1 subunit
- AMP-activated protein kinase, catalytic, alpha-1,5-AMP-activated protein kinase catalytic subunit alpha-1
- AMPK alpha 1
- AMPK alpha 1,5-AMP-activated protein kinase, catalytic alpha-1 chain
- AMPK subunit alpha-1
- AMPK
- AMPK1
- AMPKa1
- EC 2.7.11
- EC 2.7.11.1
- MGC33776
- MGC57364
- PRKAA1
- protein kinase, AMP-activated, alpha 1 catalytic subunit
Background
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.