ANP32A Antibody Summary
| Immunogen |
Rabbit anti-PHAP I polyclonal antibody was raised with a synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP I (1). This sequence is identical between human and rat PHAP I.
|
| Specificity |
PHAP I
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
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| Gene |
ANP32A
|
| Purity |
IgG purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody can be used for detection of PHAP I by Western blot at 2 to 4 ug/ml. Raji cell lysate can be used as a positive control and a band at approximately 32 kDa can be detected. It is human and mouse reactive and has no cross-reaction to PHAP I2a and PHAP III.
|
Reactivity Notes
This antibody is reactive against Human, Mouse, Rat
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
PBS
|
| Preservative |
0.02% Sodium Azide
|
| Purity |
IgG purified
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Alternate Names for ANP32A Antibody
- acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
- acidic leucine-rich nuclear phosphoprotein 32 family member A
- Acidic nuclear phosphoprotein pp32
- cerebellar leucine rich acidic nuclear protein
- I1PP2A
- inhibitor-1 of protein phosphatase-2A
- LANPPutative HLA-DR-associated protein I
- Leucine-rich acidic nuclear protein
- MAPMC15orf1
- mapmodulin
- PHAP1MGC150373
- PHAPIMGC119787
- Potent heat-stable protein phosphatase 2A inhibitor I1PP2A
- PP32
- putative human HLA class II associated protein I
Background
Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and