APJ/Apelin receptor Antibody

Product: Ecteinascidin-Analog-1

APJ/Apelin receptor Antibody Summary

Immunogen
The immunogen for this antibody is apelin receptor – C-terminal region. Peptide sequence CCDQSGCKGTPHSSSAEKSASYSSGHSQGPGPNMGKGGEQMHEKSIPYSQ.
Clonality
Polyclonal
Host
Rabbit
Gene
APLNR
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for APJ/Apelin receptor Antibody

  • AGTRL1
  • AGTRL1HG11
  • angiotensin II receptor-like 1
  • Angiotensin receptor-like 1
  • apelin receptor
  • APJ (apelin) receptor
  • APJ receptor
  • APJ
  • APJFLJ96609
  • APJR
  • APLNR
  • FLJ90771
  • G protein-coupled receptor APJ
  • G-protein coupled receptor APJ
  • G-protein coupled receptor HG11
  • HG11 orphan receptor
  • HG11
  • MGC45246

Background

Aplnr is a receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity.

PMID: 25825743

APJ/Apelin receptor Antibody

Product: PYR-41

APJ/Apelin receptor Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human Apelin Receptor.
Localization
Cell Membrane
Specificity
Human Apelin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (94%), Rat (94%), Bat (94%), Primate (94%), Monkey (100%), Rabbit (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
APLNR
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10 – 1:500
Positive Control
APJ/Apelin receptor Lysate (NBL1-07606)

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Elephant (100%), Panda (100%), Orangutan (94%), Marmoset (94%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for APJ/Apelin receptor Antibody

  • AGTRL1
  • AGTRL1HG11
  • angiotensin II receptor-like 1
  • Angiotensin receptor-like 1
  • apelin receptor
  • APJ (apelin) receptor
  • APJ receptor
  • APJ
  • APJFLJ96609
  • APJR
  • APLNR
  • FLJ90771
  • G protein-coupled receptor APJ
  • G-protein coupled receptor APJ
  • G-protein coupled receptor HG11
  • HG11 orphan receptor
  • HG11
  • MGC45246

Background

APJ or Apelin Receptor, is an angiotensin-1-like receptor that is expressed abundantly in the corpus callosum and spinal cord. The human apelin receptor has been localized to chromosome 11. In porcine spinal cord, APJ mRNA was detected at a higher level in white matter than in gray matter (Matsumoto et al., 1996). APJ binds apelin, which induces cell acidification (Tatemoto et al., 1998). APJ expression has been reported in blood, brain, spinal cord, and vessel. ESTs have been isolated from brain, head/neck, lung, and placenta libraries.

PMID: 9696401