Product: Pifithrin-β (hydrobromide)

Bcl-6 Antibody (LN22) Summary

Immunogen
Prokaryotic recombinant protein corresponding to 1-350 amino acids of the N-terminus of human Bcl-6.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Tissue culture supernatant
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Applications/Dilutions

Dilutions
  • Western Blot 1:100 – 1:2000
  • Immunohistochemistry-Frozen 1:25 – 1:50
  • Immunohistochemistry-Paraffin 1:25 – 1:50

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
No buffer
Preservative
0.05% Sodium Azide
Purity
Tissue culture supernatant

Alternate Names for Bcl-6 Antibody (LN22)

  • B-cell CLL/lymphoma 6
  • B-cell lymphoma 6 protein transcript
  • Bcl-5
  • BCL5B-cell lymphoma 5 protein
  • Bcl6
  • Bcl-6
  • BCL6A
  • cys-his2 zinc finger transcription factor
  • LAZ3
  • LAZ3ZBTB27B-cell lymphoma 6 protein
  • lymphoma-associated zinc finger gene on chromosome 3
  • Protein LAZ-3
  • ZBTB27
  • Zinc finger and BTB domain-containing protein 27
  • Zinc finger protein 51ZNF51
  • zinc finger transcription factor BCL6S
  • ZNF51

Background

This antibody reacts with the Bcl-6 gene product in follicular lymphomas, diffuse large B cell lymphomas, Burkitts lymphomas, and in nodular, lymphocyte predominant Hodgkins disease. Bcl-6 is a proto-oncogene that encodes Kruppel-type Zinc-finger protein of 95 kD and shares homology with transcription factor. Bcl-6 is mainly expressed in normal germinal center B cells and related lymphomas.

PMID: 12941441