CDC25A Antibody (3D5) Summary
| Immunogen |
CDC25A (AAH07401, 151 a.a. – 250 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTT
|
| Specificity |
CDC25A – cell division cycle 25A
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CDC25A
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for CDC25A Antibody (3D5)
- CDC25A
- CDC25A2
- CDC25A2-CAG isoform
- cell division cycle 25 homolog A (S. cerevisiae)
- cell division cycle 25 homolog A (S. pombe)
- cell division cycle 25A
- Dual specificity phosphatase Cdc25A
- EC 3.1.3.48
- M-phase inducer phosphatase 1
Background
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.