CEACAM5/CD66e Antibody (C66/1009) [Alexa Fluor® 405]

CEACAM5/CD66e Antibody (C66/1009) [Alexa Fluor® 405] Summary

Immunogen	Recombinant full-length human CEA protein
Localization	Cytoplasmic and luminal surface
Specificity	This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
Isotype	IgG2a Kappa
Clonality	Monoclonal
Host	Mouse
Gene	CEACAM1 & CEACAM5, CEACAM5
Purity	Protein A or G purified
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Applications/Dilutions

Dilutions	Flow Cytometry Immunohistochemistry-Paraffin
Application Notes	Optimal dilution of this antibody shomld be experimentally determined.

Packaging, Storage & Formulations

Storage	Store at 4C in the dark.
Buffer	50mM Sodium Borate
Preservative	0.05% Sodium Azide
Purity	Protein A or G purified

Notes

Alexa Flour (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research.

This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].

Alternate Names for CEACAM5/CD66e Antibody (C66/1009) [Alexa Fluor® 405]

Carcinoembryonic antigen
carcinoembryonic antigen-related cell adhesion molecule 5
CD66e antigen
CD66e
CEA
CEACAM5
CEACAM-5
CEACD66e
DKFZp781M2392
Meconium antigen 100

PMID: 1470919

CEACAM5/CD66e Antibody (C66/1009) [Alexa Fluor® 405]