CRHBP Antibody Summary
| Immunogen |
CRHBP (NP_001873.2, 1 a.a. – 322 a.a.) full-length human protein. MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
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| Specificity |
Reacts with corticotropin releasing hormone binding protein.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CRHBP
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| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is reactive against tissue and transfected lysate in WB and as a detection antibody in ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
Protein A purified
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Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for CRHBP Antibody
- corticotropin releasing hormone binding protein
- corticotropin-releasing factor-binding protein
- Corticotropin-releasing hormone-binding protein
- CRFBP
- CRFBPcorticotropin releasing hormone-binding protein
- CRF-BPCRF-binding protein
- CRHBP
- CRH-BP
Background
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq]