Complement C5 Antibody (C17/5) – BSA Free Summary
| Immunogen |
Purified human C5a
|
| Epitope |
Clone 05 binds to a neoepitope exposed on C5a/C5a(desArg).
|
| Specificity |
Clone C17/5 reacts with human C5a/C5a(desArg) and cross-reacts with baboon C5a/C5a(desArg).
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
C5
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Clone C17/5 reacts well with C5a/C5a(desArg). A strong reaction is seen in ELISA with recombinant C5a coated onto the microtiter well.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
10mM Phosphate (pH 7.4) and 0.5M NaCl
|
| Preservative |
15mM Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Protein A or G purified
|
Alternate Names for Complement C5 Antibody (C17/5) – BSA Free
- anaphylatoxin C5a analog
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
- C5
- complement C5
- complement component 5
- CPAMD4MGC142298
- FLJ17816
- FLJ17822
Background
Complement C5a is generated in the circulation by the activation of complement. It is a so-called anaphylatoxin of 74 amino-acid residues generated by the action of C5 convertase, which cleaves C5 into C5a and C5b. It is rapidly inactivated by serum carboxypeptidase B, which removes the C-terminal arginine residue generating C5a(desArg)