Cytochrome P450 2C18 Overexpression Lysate (Denatured) Summary
| Description |
Pasmid: pCMV-CYP2C18 full-length
|
| Gene |
CYP2C18
|
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).
|
Lysate Details for Cytochrome P450 2C18
| Type |
Overexpression
|
| Protein State |
Denatured
|
Notes
Quality control test: Transient overexpression cell lysate was tested with Anti-CYP2C18 antibody by Western Blots.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Cytochrome P450 2C18 Overexpression Lysate (Denatured)
- (S)-mephenytoin hydroxylase associated cytochrome P450
- CPCI
- CYP2C
- CYP2C17
- CYPIIC18
- cytochrome P450 2C18
- cytochrome P450, family 2, subfamily C, polypeptide 18
- cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17
- cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18
- Cytochrome P450-6b/29c
- DKFZp686I24235
- EC 1.14.14.1
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- P450-6B/29C
- P450IIC17
- unspecific monooxygenase
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]