Cytokeratin 19 Antibody (Ks19.1) [DyLight 755] Summary
| Immunogen |
Human breast cancer MCF-7 cells
|
| Localization |
Cytoplasmic
|
| Marker |
Pancreatic Stem Cell Marker
|
| Specificity |
This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
KRT19
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody shomld be experimentally determined.
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Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Notes
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for Cytokeratin 19 Antibody (Ks19.1) [DyLight 755]
- CK19
- CK-19
- Cytokeratin 19
- Cytokeratin-19,40-kDa keratin intermediate filament
- EndoC
- K19
- K19cytokeratin-19
- K1CS
- keratin 19
- keratin, type I cytoskeletal 19
- keratin, type I, 40-kd
- keratin-19
- Krt19
- MGC15366