Cytokeratin 20 Antibody (Ks20.8) Summary
| Immunogen |
Cytoskeletal preparation from micro-dissected villi of human duodenal mucosa.
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| Localization |
Cytoplasmic
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| Specificity |
This is highly specific to cytokeratin 20 and shows no cross-reaction with other intermediate filament proteins. It is essentially non-reactive in squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors
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| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
KRT20
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| Purity |
Protein A or G purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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| Theoretical MW |
48.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Positive Control |
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Reactivity Notes
Cross-reacts with Human.Not yet tested in other species.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
No buffer
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| Preservative |
Sodium Azide
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| Purity |
Protein A or G purified
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Alternate Names for Cytokeratin 20 Antibody (Ks20.8)
- CD20
- CK20
- CK-20
- cytokeratin-20
- K20cytokeratin 20
- keratin 20
- keratin, type I cytoskeletal 20
- keratin-20
- KRT21
- MGC35423
- Protein IT
Background
Cytokeratin 20 is 46 kDa intermediate filament protein that has been identified with expression primarily restricted to gastric and intestinal epithelium, urothelium, and Merkel cells. It is a unique type I keratin that is expressed in adenocarcinomas