ER alpha/NR3A1 Antibody (ESR1/420) [DyLight 650] Summary
| Immunogen |
Recombinant human ESR1 protein (aa290-560)
|
| Localization |
Nucleus
|
| Marker |
Marker of Estrogen Dependence
|
| Specificity |
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
|
| Isotype |
IgG2a
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
ESR1
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody should be experimentally determined.
|
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Notes
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for ER alpha/NR3A1 Antibody (ESR1/420) [DyLight 650]
- ER alpha
- ER
- Era
- ER-alpha
- ESR1
- ESRESRA
- Estradiol receptor
- estrogen receptor 1
- estrogen receptor alpha delta 3*4,56,7*/819-2 isoform
- estrogen receptor alpha delta 4 +49 isoform
- estrogen receptor alpha delta 4*5,6,7*/654 isoform
- estrogen receptor alpha
- estrogen receptor
- NR3A1
- NR3A1DKFZp686N23123
- Nuclear receptor subfamily 3 group A member 1