Product: Dihydrostreptomycin (sulfate)
Fc gamma RIIIA/CD16a Antibody (2B11) Summary
| Immunogen |
FCGR3A (AAH17865.1, 17 a.a. – 254 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKTNIRSSTRDWKDHKFKWRKDPQDK
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| Specificity |
FCGR3A – Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (2B11)
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| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
FCGR3A
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Fc gamma RIIIA/CD16a Antibody (2B11)
- CD16a antigen
- CD16a
- CD16FCRIIIA
- Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
- Fc gamma receptor III-A
- Fc gamma RIIIA
- FCG3
- Fc-gamma receptor III-2 (CD 16)
- Fc-gamma receptor IIIb (CD16)
- Fc-gamma RIII
- Fc-gamma RIIIa
- Fc-gamma RIII-alpha
- FCGR3
- FCGR3A
- FCGRIII
- FcgRIIIA
- FcR-10
- FCRIII
- FcRIIIa
- IGFR3FcgammaRIIIA
- immunoglobulin G Fc receptor III
- low affinity III, receptor for (CD16)
- low affinity immunoglobulin gamma Fc region receptor III-A
- neutrophil-specific antigen NA
Background
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]