GHRHR Antibody Summary
| Immunogen |
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human GHRHR.
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| Specificity |
Human GHRHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FLJ23588 (50%).
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| Predicted Species |
Canine (94%), Primate (94%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
GHRHR
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (94%), Marmoset (94%), Panda (94%), Zebu (89%), Bovine (89%), Rabbit (83%), Porcine (83%).
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.1% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for GHRHR Antibody
- GHRFR
- GHRH receptor
- GHRHR
- GRF receptor
- GRFR
- growth hormone releasing hormone receptor
- Growth hormone-releasing factor receptor
- growth hormone-releasing hormone receptor
- IGHD1B
- Little
Background
GHRHR, a Growth Hormone-Releasing Hormone Receptor, is involved in the proliferation and differentiation of somatotrophic pituitary cells and in disease. The GHRH receptor stimulates growth hormone (GH) secretion and synthesis in the pituitary. Mutations in this receptor cause either growth-hormone deficiency, resulting in dwarfism, or excessive production of the hormone, leading to gigantism. Four alternative splice variants have been identified that are tissue specific. GHRHR has been reported to be expressed primarily in the brain. ESTs have been isolated from brain and pituitary libraries.