GMPS Overexpression Lysate (Denatured) Summary
| Description |
Pasmid: pCMV-GMPS full-length
|
| Gene |
GMPS
|
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).
|
Lysate Details for GMPS
| Type |
Overexpression
|
| Protein State |
Denatured
|
Notes
Quality control test: Transient overexpression cell lysate was tested with Anti-GMPS antibody by Western Blots.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for GMPS Overexpression Lysate (Denatured)
- EC 6.3.5.2
- Glutamine amidotransferase
- GMP synthase [glutamine-hydrolyzing]
- GMP synthase
- GMP synthetase
- guanine monphosphate synthetase
- guanosine 5-monophosphate synthase
- MLL/GMPS fusion protein
Background
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq]