Galectin-1 Antibody (RM0081-9J26) Summary
| Immunogen |
Mouse recombinant Galectin-1
|
| Specificity |
This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant Galectin-1.
|
| Isotype |
IgG2
|
| Clonality |
Monoclonal
|
| Host |
Rat
|
| Gene |
LGALS1
|
| Purity |
Protein G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody detects mouse Galectin-1 in Western blotting.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
A 0.2 um filtered solution in PBS
|
| Preservative |
No Preservative
|
| Concentration |
LYOPH
|
| Purity |
Protein G purified
|
| Reconstitution Instructions |
Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.
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Alternate Names for Galectin-1 Antibody (RM0081-9J26)
- 14 kDa laminin-binding protein
- 14 kDa lectin
- Beta-galactoside-binding lectin L-14-I
- BHL
- DKFZp686E23103
- GAL1
- gal-1
- Galaptin
- galectin 1
- Galectin1
- Galectin-1
- GBP
- HBL
- HLBP14
- HPL
- L-14
- Lactose-binding lectin 1
- Lectin galactoside-binding soluble 1
- lectin, galactoside-binding, soluble, 1
- LGALS1
- Putative MAPK-activating protein PM12
- S-Lac lectin 1
Background
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin 1 may act as an autocrine negative growth factor that regulates cell proliferation. It also may regulate cell apoptosis and cell differentiation. It binds beta-galactoside, CD45, CD3 and CD4. Galectin 1 inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. It is found in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney, placenta and hematopoietic cells.