HSD17B8 Antibody Summary
| Immunogen |
HSD17B8 (AAH08185, 1 a.a. – 261 a.a.) full-length human protein. MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQINYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM
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| Specificity |
HSD17B8 – hydroxysteroid (17-beta) dehydrogenase 8,
|
| Clonality |
Polyclonal
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| Host |
Mouse
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| Gene |
HSD17B8
|
| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
Protein A purified
|
Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for HSD17B8 Antibody
- D6S2245EdJ1033B10.9
- EC 1.1.1.-
- EC 1.1.1.62
- EC 1.1.1.63,17-beta-HSD 8
- estrogen 17-oxidoreductase
- FABGLestradiol 17-beta-dehydrogenase 8
- H2-KE6
- HKE6FabG (beta-ketoacyl-[acyl-carrier-protein] reductase, E coli) like (E. coli)
- hydroxysteroid (17-beta) dehydrogenase 8,3-oxoacyl-[acyl-carrier-protein] reductase
- KE6
- ke-6
- Ke-6,17-beta-hydroxysteroid dehydrogenase 8
- Protein Ke6
- Really interesting new gene 2 protein
- RING2FABG
- SDR30C1
- short chain dehydrogenase/reductase family 30C, member 1
- Testosterone 17-beta-dehydrogenase 8
Background
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq]