ILT5/CD85a/LILRB3 Antibody (4F9) [DyLight 755] Summary
| Immunogen |
Monocyte derived dendritic cells
|
| Specificity |
NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
LILRB3
|
| Purity |
Protein G purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Optimal dilution of this antibody should be experimentally determined.
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Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
50mM Sodium Borate
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein G purified
|
Notes
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for ILT5/CD85a/LILRB3 Antibody (4F9) [DyLight 755]
- CD85 antigen-like family member A
- CD85a antigen
- CD85a
- HL9Immunoglobulin-like transcript 5
- ILT5
- ILT-5
- ILT5CD85a
- Leukocyte immunoglobulin-like receptor 3
- leukocyte immunoglobulin-like receptor subfamily B member 3
- leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains)
- LILRB3
- LIR3
- LIR3CD85A
- LIR-3MGC138403
- member 3
- Monocyte inhibitory receptor HL9
- PIRB