Product: Piperoxan (hydrochloride)
IL-17F Antibody Summary
| Immunogen |
This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant mouse IL17-F protein.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
IL17F
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
IL-17F antibody has been heated to 56 degrees C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant mouse IL17-F in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
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Reactivity Notes
Mouse, Rat.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
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| Preservative |
No Preservative
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| Concentration |
LYOPH
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| Purity |
Immunogen affinity purified
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| Reconstitution Instructions |
Reconstitute with 0.1 ml deionized water to a final concentration of 5.0 mg/ml.
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Alternate Names for IL-17F Antibody
- Cytokine ML-1
- IL17F
- IL-17F
- IL-17Finterleukin-17F
- IL24
- IL-24
- interleukin 17F
- Interleukin-24
- ML-1
- ML1interleukin-24
Background
IL17-F (also known as ML1, ML-1, IL17F, and IL24) is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angio-genesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/ GFB, and monocyte chemoattractant protein-1. IL-17F plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation. Anti-IL-17F antibody is ideal for investigators involved in Cardiovascular and Immunology research.