IP6K1 Antibody Summary
| Immunogen |
Synthetic Peptide: P(216) C V L D L K M G T R Q H G D D A S(233).
|
| Specificity |
NB120-3524 detects inositol-hexakisphosphate kinase (IP6 kinase) from rat tissues.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
IP6K1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
WB: Detects an approx. 50 kDa protein representing IP6 kinase from rat brain extract.
|
Reactivity Notes
Expected cross-reactivity with Human base on sequence homology.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.05% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for IP6K1 Antibody
- ATP:1D-myo-inositol-hexakisphosphate phosphotransferase
- EC 2.7.4.21
- inositol hexakisphosphate kinase 1
- Inositol hexaphosphate kinase 1KIAA0263IHPK1PiUS
- InsP6 kinase 1
- MGC9925
- Pi uptake stimulator
Background
Inositol 1,4,5-trisphosphate (IP3) is a second messenger for many growth factors, hormones, and neurotransmitters and, upon binding to the IP3 receptor (IP3R), triggers the release of intracellular, luminal calcium to the cytosol. Several additional cellular forms of inositol phosphates have been discovered. These include some which have been recently discovered and characterized to possess up to seven or eight phosphate groups, including pyrophosphates (PP-IPs: pyrophosphate-inositol phosphates). It has been proposed that high-energy pyrophosphates may participate in protein phosphorylation. Inositol Hexakisphosphate (IP6) Kinase, or PiUS (Pi Uptake Stimulator) has ATP synthase activity and transfers a phosphate from PP-IP5 to ADP to form ATP thus suggesting an important physiological role for PP-IP5 and IP6 kinase.