KCNA7 Antibody Summary
| Immunogen |
Synthetic peptide derived from C-terminal domain of KCNA7 protein
|
| Specificity |
Reacts specifically with human 50 kDa protein
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
KCNA7
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human, Mouse and Rat.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris, 0.1M Glycine and 2% Sucrose
|
| Preservative |
No Preservative
|
| Concentration |
LYOPH
|
| Purity |
Protein A purified
|
| Reconstitution Instructions |
Reconstitute with distilled water.
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Alternate Names for KCNA7 Antibody
- HAK6
- KV1.7
- potassium voltage-gated channel subfamily A member 7
- potassium voltage-gated channel, shaker-related subfamily, member 7
- voltage-dependent potassium channel Kv1.7
- voltage-gated potassium channel KCNA7
- Voltage-gated potassium channel subunit Kv1.7
Background
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. The gene is expressed preferentially in skeletal muscle, heart and kidney. It is a candidate gene for inherited cardiac disorders.