Product: Debutyldronedarone D7

NAT2 Antibody Summary

Immunogen
Synthetic peptides corresponding to NAT2 (N-acetyltransferase 2 (arylamine N-acetyltransferase)) The peptide sequence was selected from the middle region of NAT2)(50ug).Peptide sequence TYRKFNYKDNTDLVEFKTLTEEEVEEVLRNIFKISLGRNLVPKPGDGSLT.
Clonality
Polyclonal
Host
Rabbit
Gene
NAT2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against NAT2 and was validated on Western blot.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for NAT2 Antibody

  • AAC2N-acetyltransferase type 2
  • Arylamide acetylase 2
  • arylamine N-acetyltransferase 2
  • EC 2.3.1.5
  • N-acetyltransferase 2 (arylamine N-acetyltransferase)
  • NAT-2
  • PNAT
  • Polymorphic arylamine N-acetyltransferase

Background

NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.

PMID: 16308421

Product: Famprofazone

NAT2 Antibody Summary

Immunogen
NAT2 (AAH15878.1, 1 a.a. – 290 a.a.) full-length human protein. MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPQTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI
Specificity
Reacts with N-acetyltransferase 2 (arylamine N-acetyltransferase).
Clonality
Polyclonal
Host
Mouse
Gene
NAT2
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This antibody is reactive against tissue and transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NAT2 Antibody

  • AAC2N-acetyltransferase type 2
  • Arylamide acetylase 2
  • arylamine N-acetyltransferase 2
  • EC 2.3.1.5
  • N-acetyltransferase 2 (arylamine N-acetyltransferase)
  • NAT-2
  • PNAT
  • Polymorphic arylamine N-acetyltransferase

Background

This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq]

PMID: 23382385