PPAR alpha/NR1C1 Antibody (1A8) Summary
| Immunogen |
PPARA (AAH00052, 1 a.a. – 258 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGRSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPVGVCGCSGFSWQHGTSVVEDD
|
| Specificity |
PPARA – peroxisome proliferative activated receptor, alpha (1A8)
|
| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
PPARA
|
| Purity |
IgG purified
|
| Innovators Reward |
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Applications/Dilutions
| Dilutions |
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| Application Notes |
It has been used for ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PPAR alpha/NR1C1 Antibody (1A8)
- alpha
- hPPAR
- NR1C1
- NR1C1MGC2237
- Nuclear receptor subfamily 1 group C member 1
- peroxisome proliferator-activated receptor alpha
- PPAR alpha
- PPARA
- PPARalpha
- PPAR-alpha
- PPARMGC2452
Background
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq]