Product: Alfuzosin (hydrochloride)
Phospholipid Scramblase 1/PLSCR1 Antibody Summary
| Immunogen |
This antibody is specific for the N Terminus Region of the target protein.
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| Specificity |
This product is specific for Human PLSCR1.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
PLSCR1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in ELISA.
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| Publications |
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Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
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| Preservative |
No Preservative
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| Purity |
Immunogen affinity purified
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Notes
Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.
Alternate Names for Phospholipid Scramblase 1/PLSCR1 Antibody
- Erythrocyte phospholipid scramblase
- MMTRA1B
- MMTRA1BCa(2+)-dependent phospholipid scramblase 1
- Phospholipid Scramblase 1
- PL scramblase 1
- PLSCR1
Background
Phospholipid scramblase 1 (PLSCR1) is a member of the PLSCR protein family. These proteins are ATP-independent lipid translocators localized to the plasma membrane and is involved in a calcium dependent, nonspecific and rapid redistribution (scrambling) of phospholipids when a perturbation of plasma membrane asymmetry is needed for the cell (e.g. following cell activation, injury, or apoptosis). The expression of PLSCR1 is found in a variety of tissue and can be stress-induced. Upon stimulation (e.g. interferon stimulation), a portion of newly synthesized PLSCR1 is imported into the nucleus (instead of inserted into the plasma membrane) and interacts with DNA, consistent with a role in gene regulation. PLSCR1 may be closely associated with the pathophysiology underlying infection and inflammation, which manifest marked changes in energy consumption and lipid metabolism.