Rap2A Antibody Summary
| Immunogen |
The immunogen for this antibody is RAP2A – N-terminal region. Peptide sequence KYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFIL.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
RAP2A
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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| Theoretical MW |
20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
PBS and 2% Sucrose
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| Preservative |
0.09% Sodium Azide
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| Purity |
Immunogen affinity purified
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Notes
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Alternate Names for Rap2A Antibody
- KREV
- K-REV
- RAP2
- RAP2, member of RAS oncogene family (K-rev)
- Rap2A
- RAP2A, member of RAS oncogene family
- ras-related protein Rap-2a
- RbBP-30
Background
RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.