Product: Tedizolid (phosphate)
Recombinant Human BMPR-II Protein Summary
| Description |
BMPR-II (Human) GST-Tagged Recombinant Protein
Source: Wheat Germ (in vitro) Amino Acid Sequence: NSLDLSATNVLDGSSIQIGESTQDGKSGSGEKIKKRVKTPYSLKRWRPSTWVISTESLDCEVNNNGSNRAVHSKSSTAVYLAEGGTATTMVSKDIGMNC |
| Details of Functionality |
This protein is not active and should not be used for experiments requiring activity.
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| Protein/Peptide Type |
Partial Recombinant Protein
|
| Gene |
BMPR2
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Applications/Dilutions
| Application Notes |
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
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| Buffer |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
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Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human BMPR-II Protein
- BMP type II receptor
- BMP type-2 receptor
- BMPR2
- BMPR-2
- BMPR3
- BMPRII
- BMPR-II
- BMPR-IIprimary pulmonary hypertension 1
- Bone morphogenetic protein receptor type II
- bone morphogenetic protein receptor type-2
- bone morphogenetic protein receptor, type II (serine/threonine kinase)
- BRK-3
- EC 2.7.11
- EC 2.7.11.30
- FLJ41585
- FLJ76945
- PPH1BMR2
- T-ALK
- type II activin receptor-like kinase
- type II receptor for bone morphogenetic protein-4
Background
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq]