Product: Vinflunine (Tartrate)

SNRPB Antibody Summary

Immunogen
Synthetic peptides corresponding to SNRPB(small nuclear ribonucleoprotein polypeptides B and B1) The peptide sequence was selected from the middle region of SNRPB.Peptide sequence LRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMP.
Clonality
Polyclonal
Host
Rabbit
Gene
SNRPB
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against SNRPB and was validated on Western blot.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS & 2% Sucrose.
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for SNRPB Antibody

  • CODB polypeptide of Sm protein
  • Sm protein B/B
  • small nuclear ribonucleoprotein polypeptides B and B
  • small nuclear ribonucleoprotein polypeptides B and B1
  • small nuclear ribonucleoprotein-associated proteins B and B
  • SmB/B
  • Sm-B/Bsm-B/Sm-B
  • SmB/SmB
  • snRNP-Bsmall nuclear ribonucleoprotein polypeptide B
  • SNRPB1

Background

SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B) have been found for this gene.

PMID: 17202480