SPTLC1 Antibody (3D11) Summary
| Immunogen |
SPTLC1 (AAH07085, 43 a.a. ~ 144 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.TYKLQERSDLTVKEKEELIEEWQPEPLVPPVPKDHPALNYNIVSGPPSHKTVVNGKECINFASFNFLGLLDNPRVKAATLASLKKYGVGTCGPRGFYGTFE
|
| Specificity |
Reacts with serine palmitoyltransferase, long chain base subunit 1.
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
SPTLC1
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is reactive against recombinant protein in western blot and ELISA.
|
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Protein A purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for SPTLC1 Antibody (3D11)
- EC 2.3.1.50
- hereditary sensory neuropathy, type 1
- HSAN1
- LBC1
- LCB 1
- LCB1HSAN
- Long chain base biosynthesis protein 1
- MGC14645
- serine C-palmitoyltransferase
- serine palmitoyltransferase 1
- serine palmitoyltransferase, long chain base subunit 1
- Serine-palmitoyl-CoA transferase 1
- SPT 1
- SPT1HSN1
- SPTI
Background
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq]