Sirtuin 2/SIRT2 Antibody Summary
| Immunogen |
SIRT2 (NP_085096.1, 1 a.a. ~ 352 a.a) full-length human protein.MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQ
|
| Marker |
Early Oligodendrocyte Marker
|
| Specificity |
SIRT2 – sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae),
|
| Clonality |
Polyclonal
|
| Host |
Mouse
|
| Gene |
SIRT2
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against transfected lysate for western blot and recombinant protein with GST tag for ELISA and Western Blot. GST tag alone is used as a negative control.
|
Reactivity Notes
Human.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Protein A purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Sirtuin 2/SIRT2 Antibody
- EC 3.5.1
- EC 3.5.1.-
- FLJ35621
- FLJ37491
- S.cerevisiae, homolog) 2
- SIR2L2
- SIRT2
- Sirtuin 2
- sirtuin type 2
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene. [provided by RefSeq]