TAG-72 Antibody (CA72/145)

Product: Imipramine (hydrochloride)

TAG-72 Antibody (CA72/145) Summary

Immunogen
Human CA72.4 protein
Localization
Cytoplasmic and cell surface
Specificity
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.5 – 1.0 ug/ml
  • Flow Cytometry 0.5 – 1 ug/million cells in 0.1 ml
  • Immunoprecipitation 1 – 2 ug/500 ug Protein Lysate
  • Immunofluorescence 1 – 2 ug/ml
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
220 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10mM PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for TAG-72 Antibody (CA72/145)

  • CA 72-4
  • Protein TAG-72
  • tag 72
  • tag-72 Protein TAG-72

PMID: 22044162