TGF-alpha Antibody (TGFA/1119)

Recombinant human full-length TGF alpha protein

Cytoplasmic and Extracellular (secreted)

This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

IgG1 Kappa

Monoclonal

Mouse

TGFA

Protein A or G purified

Test in a species/application not listed above to receive a full credit towards a future purchase.

Hu-chromosome location: 2p13.3
Molecular weight of antigen: ~6kDa
Immunohistology Formalin-paraffin 2 – 4 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10 – 20 min followed by cooling at RT for 20 minutes.