Troponin T Type 2 (cardiac) Antibody (BGN/1288/44) Summary
| Immunogen |
HMW conjugate
|
| Epitope |
F-M-P-N-L-V-P-P-K-I-C
|
| Localization |
Cytoplasmic
|
| Specificity |
NB100-66490 recognises Troponin T Type 2 (cardiac) isoform 1. In Western blotting, this reacts with reduced purified cardiac isoform, but does not react with the skeletal isoform.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TNNT2
|
| Purity |
Protein A purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.2)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein A purified
|
Alternate Names for Troponin T Type 2 (cardiac) Antibody (BGN/1288/44)
- cardiac
- CMD1D
- CMPD2
- dilated 1D (autosomal dominant)
- hypertrophic 2
- MGC3889
- RCM3
- TnTc
- troponin T type 2 (cardiac)
- troponin T, cardiac muscle
Background
Cardiac Troponin T, a 36kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.