U2AF2 Antibody Summary
| Immunogen |
Synthetic peptides corresponding to U2AF2 (U2 small nuclear RNA auxiliary factor 2) The peptide sequence was selected from the N terminal of U2AF2.Peptide sequence EFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSAS.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
U2AF2
|
| Purity |
Protein A purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This is a rabbit polyclonal antibody against U2AF2 and was validated on Western blot.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Theoretical MW |
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS and 2% Sucrose
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| Preservative |
0.09% Sodium Azide
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| Purity |
Protein A purified
|
Notes
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Alternate Names for U2AF2 Antibody
- hU2AF(65)
- hU2AF65
- splicing factor U2AF 65 kD subunit
- splicing factor U2AF 65 kDa subunit
- U2 (RNU2) small nuclear RNA auxiliary factor 2
- U2 auxiliary factor 65 kDa subunit
- U2 small nuclear ribonucleoprotein auxiliary factor (65kD)
- U2 small nuclear RNA auxiliary factor 2
- U2AF65U2 snRNP auxiliary factor large subunit
Background
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.