VEGF-B Antibody (RM0008-6E72) Summary
| Immunogen |
This antibody was produced from a hybridoma (mouse myeloma fused withspleen cells from a rat immunized with purified mouse VEGF-B (186).
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| Specificity |
VEGFB (RM0008-6E72)
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| Isotype |
IgG2
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| Clonality |
Monoclonal
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| Host |
Rat
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| Gene |
VEGFB
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| Purity |
Protein G purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody recognizes mouse VEGF-B 186 but not 167.
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Reactivity Notes
This antibody is reactive against mouse. Not yet tested in other species.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
A 0.2 um filtered solution in PBS
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| Preservative |
No Preservative
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| Concentration |
LYOPH
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| Purity |
Protein G purified
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| Reconstitution Instructions |
Reconstitute with 0.5 ml sterilized PBS to a final concentration of 0.2 mg/ml.
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Alternate Names for VEGF-B Antibody (RM0008-6E72)
- vascular endothelial growth factor B
- VEGFB
- VEGF-B
- VEGF-related factor
- VRFVEGFL
Background
VEGFB 186 is an isoform of VEGFB (Vascular Endothelial Growth Factor B), a member of the vascular endothelial growth factor (VEGF) family. It is a growth factor for endothelial cells. Both isoforms of VEGFB show strong homology to VEGF at their amino termini, wheras the VEGFB167 isoform binds heparin, the C terminus of VEGFB-186 has no heparin binding domain, is less basic and more hydrophobic, and has no similarity to any published sequence. VEGFB 186 is secreted as a disulfide-linked homodimer and that, like VEGFB 167, this isoform can form disulfide-linked heterodimers with VEGF.