Product: Alosetron (D3 Hydrochloride)
Vang-like Protein 2/VANGL2 Antibody Summary
| Immunogen |
Synthetic peptide derived from N-terminal domain of human VANGL2 protein
|
| Specificity |
Reacts with human 60 kDa VANGL2 protein.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
VANGL2
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Human, Mouse and Rat.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris, 0.1M Glycine and 2% Sucrose
|
| Preservative |
No Preservative
|
| Concentration |
LYOPH
|
| Purity |
Protein A purified
|
| Reconstitution Instructions |
Reconstitute with distilled water.
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Alternate Names for Vang-like Protein 2/VANGL2 Antibody
- KIAA1215Loop-tail protein 1 homolog
- loop-tail-associated protein
- LPP1
- LTAP
- LTAPVan Gogh-like protein 2
- MGC119403
- MGC119404
- STB1
- STB1Strabismus 1
- STBM
- STBM1
- Strabismus
- vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila)
- Vang like Protein 2
- VANGL2
- vang-like 2 (van gogh, Drosophila)
- Vang-like Protein 2
Background
VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.The VANGL2 gene encodes a homolog of Drosophila strabismus/Van Gogh (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]