Product: Kevetrin (hydrochloride)
n-Myc Antibody Summary
| Immunogen |
MYCN (NP_005369.2, 1 a.a. – 464 a.a.) full-length human protein. MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC
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| Specificity |
MYCN – v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian),
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
MYCN
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| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
Protein A purified
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Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for n-Myc Antibody
- BHLHE37
- bHLHe37N-myc proto-oncogene protein
- Class E basic helix-loop-helix protein 37
- MODED
- neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene
- N-myc
- NMYCneuroblastoma MYC oncogene
- ODED
- oncogene NMYC
- pp65/67
- v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
- v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Background
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq]