All content so that it is actually useful to a significantly wider population. The European principles of management of headache disorders in primary care, laid out in 11 sections, will be the core on the content. Every of those is more-or-less stand-alone, so that you can act as practicalThe Journal of Headache and Discomfort 2017, 18(Suppl 1):Web page ten ofmanagement aids at the same time as educational resources. There is a set of additional sensible management aids. An abbreviated version from the International Classification of Headache Disorders, 3rd edition (ICHD3), supplies diagnostic criteria for the few headache problems relevant to principal care. A headache diary additional assists diagnosis and also a headache calendar assists follow-up. A measure of headache effect (the HALT-90 index) can be employed in pre-treatment assessment of illness severity, and an outcome measure (the HURT questionnaire) can be a guide to follow-up and need to have for treatment-review. 5 patient information and facts leaflets are incorporated, which could be supplied to patients to improve their understanding of their headache issues and their management. LTB and EHF present these aids freely offered for use without restriction. We hope for advantages for both physicians and patients. S33 Combined hormonal contraception and migraine, WHO and EHF ESCRH criteria and balancing risks and benefit Simona Sacco ([email protected]) Neurology section, Division of Applied Clinical Science and Biotechnology, University of L’Aquila, L’Aquila, Italy The Journal of Headache and Pain 2017, 18(Suppl 1):S33 Many information indicate that migraine, in particular migraine with aura, is associated with an Homotaurine Protocol elevated risk of ischemic stroke and other vascular events. Of concern is no matter whether the threat of ischemic stroke in migraineurs is magnified by the usage of hormonal contraceptives (HCs). As migraine prevalence is high in women of reproductive age, it’s widespread to face the issue of migraine and HC use in clinical practice. To improve decision-making on the use of HCs in females with migraine, a selected group of representatives from the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Overall health (ESC) developed a Consensus Statement on this subject. The document pointed out that proof addressing the risk of ischemic stroke linked using the use of HCs is generally poor. All information relies on observational information, which may carry the risk of potential bias. Offered studies had distinctive settings and employed unique groups for comparing dangers, limiting reputable comparison of research as a pooled analysis of data. Many of the offered research were published several years ago and applied compounds that are distinct from these out there today. Also, in most studies not sufficient data is offered relating to the type of HC regarded as and in most instances benefits aren’t provided in accordance with migraine sort. Regardless of those limitations, out there data pointed toward an increased threat of ischemic stroke related with all the use of HCs in girls with migraine. Literature indicated that, whereas combined HCs carry a particular danger of arterial ischemic events this will not take place for progestogens-only HCs which are viewed as safe in terms of cardiovascular threat even inside the Cholesteryl Linolenate Endogenous Metabolite presence of associated danger factors. Taking into consideration those data, and unless research will prove safety on the use of combined HCs in females with migraine, the suggestions in the Consensus Group gave priority to security and recommended quite a few limit.