E pharmacy warehouse for stocks of fomepizole, which had been out there and delivered for the ICU-satellite pharmacy within 7 hours from the initial fomepizole order for the index case. Figure 1 outlines the pharmaceutical distribution procedure at our institution. The toxicologists overseeing the patient had also inquired the pharmacy regarding the availability of ethanol (an option antidote for methanol toxicity), which was regrettably not listed as a formulary item and was only stocked in the narcotic pharmacy in small quantities for other uses, and pharmacy employees were not conscious of its availability. Figure two outlines the timeline and sequence of the event.Frontiers in Pharmacologyfrontiersin.orgAbu Esba et al.ten.3389/fphar.2022.FIGURE 1 Timeline and sequence with the occasion.MethodSetting: King Abdulaziz Healthcare City (KAMC) can be a 1500bed tertiary care hospital in Riyadh, Saudi Arabia, and is below the umbrella of your huge integrated overall health program of the Ministry of National Guard Health Affairs, which contains six health-related cities. The hospital has emergency services, specialized toxicology physicians, a drug and poison information center (DPIC) and its laboratory service is nicely equipped to perform all important toxicology testing. The medication safety program can be a well-established division of your good quality and patient safety department at KAMC, and is responsible for monitoring and analyzing all reported medication adverse events, routinely conducts RCA and identifies areas for improvement, and recommends actions to stop patient harm.All suggestions are discussed in a collective corporate meeting such as all regional hospitals, and agreed-upon suggestions are implemented in all hospitals.The root lead to evaluation processThe delay in allocation and remedy of patients presenting with methanol toxicity was discussed in our pharmacy and therapeutics committee and also a memo was sent to our good quality and patient safety department to officially conduct an RCA and respond to our committee with benefits for improvement and actions to be taken. A group of 16 members was formed to conduct the RCA and incorporated: medication safety officers (team leader), qualityFrontiers in Pharmacologyfrontiersin.orgAbu Esba et al.ten.3389/fphar.2022.FIGURE two Pharmaceutical Distribution Course of action at MNGHA.Frontiers in Pharmacologyfrontiersin.NH125 supplier orgAbu Esba et al.Methoprene Epigenetic Reader Domain ten.3389/fphar.2022.improvement specialists, ER consultant, a toxicologist, a nursing medication security representative, the DPIC pharmacist, director from the pharmaceutical organizing department, and the director of warehousing and distribution. Also for the primary RCA meeting, a number of person interviews with all the stakeholders and inspection visits to the region had been conducted.PMID:23443926 The institutional critique board (IRB) at King Abdullah International Healthcare Study Center (KAIMRC) (Protocol NRC21R/520/12) authorized this study. No consent form was required by the Ministry of National Guard Overall health Affairs ethics committee.Therefore, the root cause of this deviation was inappropriate location style. three) Communication aspects: The sound-alike amongst fomepizole and omeprazole led the ICU pharmacist to inform the ER pharmacy technician that fomepizole was not out there in stock; this was a verbal miscommunication over the phone. The delay in response in the on-call pharmacist within the pharmacy key retailer as well as the misinformation in regards to the availability of stocks inside the pharmacy warehouse led the rest from the efforts to focus on borro.