Product Name :
Oglemilast
Description:
Oglemilast, also known as GRC 3886, is a potent and selective PDE4 inhibitor (IC50: 2.5 nM (PDE4B) and 1.7 nM (PDE4D)). Oglemilast was a drug under development to treat chronic obstructive pulmonary disorder (COPD)—a lung disease—and asthma. In 2009, Phase IIb trials was failed.
CAS:
778576-62-8
Molecular Weight:
516.30
Formula:
C20H13Cl2F2N3O5S
Chemical Name:
N-(3,5-dichloropyridin-4-yl)-6-(difluoromethoxy)-12-methanesulfonamido-8-oxatricyclo[7.4.0.0²,⁷]trideca-1(9),2,4,6,10,12-hexaene-3-carboxamide
Smiles :
CS(=O)(=O)NC1C=C2C3=C(C=CC(OC(F)F)=C3OC2=CC=1)C(=O)NC1=C(Cl)C=NC=C1Cl
InChiKey:
OKFDRAHPFKMAJH-UHFFFAOYSA-N
InChi :
InChI=1S/C20H13Cl2F2N3O5S/c1-33(29,30)27-9-2-4-14-11(6-9)16-10(3-5-15(18(16)31-14)32-20(23)24)19(28)26-17-12(21)7-25-8-13(17)22/h2-8,20,27H,1H3,(H,25,26,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Oglemilast, also known as GRC 3886, is a potent and selective PDE4 inhibitor (IC50: 2.5 nM (PDE4B) and 1.7 nM (PDE4D)). Oglemilast was a drug under development to treat chronic obstructive pulmonary disorder (COPD)—a lung disease—and asthma. In 2009, Phase IIb trials was failed.|Product information|CAS Number: 778576-62-8|Molecular Weight: 516.30|Formula: C20H13Cl2F2N3O5S|Chemical Name: N-(3,5-dichloropyridin-4-yl)-6-(difluoromethoxy)-12-methanesulfonamido-8-oxatricyclo[7.{{Cefpodoxime} web|{Cefpodoxime} Bacterial|{Cefpodoxime} Biological Activity|{Cefpodoxime} Purity|{Cefpodoxime} custom synthesis|{Cefpodoxime} Autophagy} 4.{{Daptomycin} medchemexpress|{Daptomycin} Anti-infection|{Daptomycin} Technical Information|{Daptomycin} In Vitro|{Daptomycin} supplier|{Daptomycin} Epigenetics} 0.PMID:32695810 0²,⁷]trideca-1(9),2,4,6,10,12-hexaene-3-carboxamide|Smiles: CS(=O)(=O)NC1C=C2C3=C(C=CC(OC(F)F)=C3OC2=CC=1)C(=O)NC1=C(Cl)C=NC=C1Cl|InChiKey: OKFDRAHPFKMAJH-UHFFFAOYSA-N|InChi: InChI=1S/C20H13Cl2F2N3O5S/c1-33(29,30)27-9-2-4-14-11(6-9)16-10(3-5-15(18(16)31-14)32-20(23)24)19(28)26-17-12(21)7-25-8-13(17)22/h2-8,20,27H,1H3,(H,25,26,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
