Product Name :
LLS30
Description:
LLS30 is an allosteric inhibitor of Galectin-1 (Gal-1). LLS30 decreases Gal-1 binding affinity to its binding partners, and potentially overcomes metastatic castration-resistant prostate cancer (mCRPC).
CAS:
2138367-58-3
Molecular Weight:
701.47
Formula:
C34H33Cl4N5O3
Chemical Name:
3-(2-(4-(Bis(2-hydroxyethyl)amino)phenyl)-1-(3, 4-dichlorobenzyl)-1H-benzo[d]imidazol-5-yl)-3-((3, 4-dichlorobenzyl)amino)propanamide
Smiles :
NC(=O)CC(NCC1=CC(Cl)=C(Cl)C=C1)C1C=C2N=C(C3C=CC(=CC=3)N(CCO)CCO)N(CC3=CC(Cl)=C(Cl)C=C3)C2=CC=1
InChiKey:
XWBTXDFCKRACTA-UHFFFAOYSA-N
InChi :
InChI=1S/C34H33Cl4N5O3/c35-26-8-1-21(15-28(26)37)19-40-30(18-33(39)46)24-5-10-32-31(17-24)41-34(43(32)20-22-2-9-27(36)29(38)16-22)23-3-6-25(7-4-23)42(11-13-44)12-14-45/h1-10,15-17,30,40,44-45H,11-14,18-20H2,(H2,39,46)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Vactosertib} MedChemExpress|{Vactosertib} TGF-β Receptor|{Vactosertib} NF-κB|{Vactosertib} Purity & Documentation|{Vactosertib} In stock|{Vactosertib} custom synthesis}
Shelf Life:
≥12 months if stored properly.{{Neomycin} medchemexpress|{Neomycin} Anti-infection|{Neomycin} Protocol|{Neomycin} Formula|{Neomycin} supplier|{Neomycin} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
LLS30 is an allosteric inhibitor of Galectin-1 (Gal-1). LLS30 decreases Gal-1 binding affinity to its binding partners, and potentially overcomes metastatic castration-resistant prostate cancer (mCRPC).|Product information|CAS Number: 2138367-58-3|Molecular Weight: 701.47|Formula: C34H33Cl4N5O3|Chemical Name: 3-(2-(4-(Bis(2-hydroxyethyl)amino)phenyl)-1-(3, 4-dichlorobenzyl)-1H-benzo[d]imidazol-5-yl)-3-((3, 4-dichlorobenzyl)amino)propanamide|Smiles: NC(=O)CC(NCC1=CC(Cl)=C(Cl)C=C1)C1C=C2N=C(C3C=CC(=CC=3)N(CCO)CCO)N(CC3=CC(Cl)=C(Cl)C=C3)C2=CC=1|InChiKey: XWBTXDFCKRACTA-UHFFFAOYSA-N|InChi: InChI=1S/C34H33Cl4N5O3/c35-26-8-1-21(15-28(26)37)19-40-30(18-33(39)46)24-5-10-32-31(17-24)41-34(43(32)20-22-2-9-27(36)29(38)16-22)23-3-6-25(7-4-23)42(11-13-44)12-14-45/h1-10,15-17,30,40,44-45H,11-14,18-20H2,(H2,39,46)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24367939 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Shih TC, Liu R, Wu CT, Li X, Xiao W, Deng X, Kiss S, Wang T, Chen XJ, Carney R, Kung HJ, Duan Y, Ghosh PM, Lam KS. Targeting Galectin-1 Impairs Castration-Resistant Prostate Cancer Progression and Invasion. Clin Cancer Res. 2018 Sep 1;24(17):4319-4331. doi: 10.1158/1078-0432.CCR-18-0157. Epub 2018 Apr 17. PubMed PMID: 29666302; PubMed Central PMCID: PMC6125207.Products are for research use only. Not for human use.|
