Product Name :
DUN71755
Description:
DUN71755, also known as nAChR agonist 1, is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). DUN71755 is reported in WO 2012114285.
CAS:
1394371-75-5
Molecular Weight:
419.94
Formula:
C20H18ClNO3S2
Chemical Name:
4-(5-(4-chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide
Smiles :
CC1C(=C(SC=1C1C=CC(Cl)=CC=1)C(=O)CC)C1C=CC(=CC=1)S(N)(=O)=O
InChiKey:
DYIIYIJHDMIABW-UHFFFAOYSA-N
InChi :
InChI=1S/C20H18ClNO3S2/c1-3-17(23)20-18(13-6-10-16(11-7-13)27(22,24)25)12(2)19(26-20)14-4-8-15(21)9-5-14/h4-11H,3H2,1-2H3,(H2,22,24,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
DUN71755, also known as nAChR agonist 1, is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). DUN71755 is reported in WO 2012114285. |Product information|CAS Number: 1394371-75-5|Molecular Weight: 419.94|Formula: C20H18ClNO3S2|Synonym:|DUN-71755|nAChR agonist 1|DUN71755|DUN 71755|Chemical Name: 4-(5-(4-chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide|Smiles: CC1C(=C(SC=1C1C=CC(Cl)=CC=1)C(=O)CC)C1C=CC(=CC=1)S(N)(=O)=O|InChiKey: DYIIYIJHDMIABW-UHFFFAOYSA-N|InChi: InChI=1S/C20H18ClNO3S2/c1-3-17(23)20-18(13-6-10-16(11-7-13)27(22,24)25)12(2)19(26-20)14-4-8-15(21)9-5-14/h4-11H,3H2,1-2H3,(H2,22,24,25)|Technical Data|Appearance: Solid Power.{{[Leu5]-Enkephalin} web|{[Leu5]-Enkephalin} Neuronal Signaling|{[Leu5]-Enkephalin} Biological Activity|{[Leu5]-Enkephalin} In stock|{[Leu5]-Enkephalin} supplier|{[Leu5]-Enkephalin} Epigenetic Reader Domain} |Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Clemizole} web|{Clemizole} TRP Channel|{Clemizole} Activator|{Clemizole} Technical Information|{Clemizole} Formula|{Clemizole} manufacturer} |Shelf Life: ≥360 days if stored properly.PMID:24318587 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|References:|Sinha N, et al.Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization. J Med Chem. 2020 Feb 13;63(3):944-960.Products are for research use only. Not for human use.|
