Product Name :
Biperiden
Description:
AZD8186 is and inhibitor of the beta isoform of phosphoinositide-3 kinase (PI3K), with potential antineoplastic activity. Upon administration, PI3Kbeta inhibitor AZD8186 selectively inhibits the activity of PI3Kbeta in the PI3K/Akt/mTOR signaling pathway, which may result in a decrease of tumor cell proliferation. It also induces cell death in PI3K-expressing cancer cells. By specifically targeting class I PI3K beta, this agent may be more efficacious and less toxic than pan PI3K inhibitors. PI3K-mediated signaling is often dysregulated in cancer cells and contributes to increased tumor cell growth, survival, and tumor resistance to a variety of antineoplastic agents. AZD8186 is currently under Phase I clinical trials.
CAS:
514-65-8
Molecular Weight:
311.46
Formula:
C21H29NO
Chemical Name:
1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol
Smiles :
OC(CCN1CCCCC1)(C1CC2CC1C=C2)C1C=CC=CC=1
InChiKey:
YSXKPIUOCJLQIE-UHFFFAOYSA-N
InChi :
InChI=1S/C21H29NO/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
AZD8186 is and inhibitor of the beta isoform of phosphoinositide-3 kinase (PI3K), with potential antineoplastic activity. Upon administration, PI3Kbeta inhibitor AZD8186 selectively inhibits the activity of PI3Kbeta in the PI3K/Akt/mTOR signaling pathway, which may result in a decrease of tumor cell proliferation. It also induces cell death in PI3K-expressing cancer cells. By specifically targeting class I PI3K beta, this agent may be more efficacious and less toxic than pan PI3K inhibitors. PI3K-mediated signaling is often dysregulated in cancer cells and contributes to increased tumor cell growth, survival, and tumor resistance to a variety of antineoplastic agents.{{Sodium metatungstate} MedChemExpress|{Sodium metatungstate} GPCR/G Protein|{Sodium metatungstate} NF-κB|{Sodium metatungstate} Protocol|{Sodium metatungstate} In stock|{Sodium metatungstate} manufacturer} AZD8186 is currently under Phase I clinical trials.|Product information|CAS Number: 514-65-8|Molecular Weight: 311.46|Formula: C21H29NO|Synonym:|Akineton|KL 373|Chemical Name: 1-{bicyclo[2.{{Teprotumumab} web|{Teprotumumab} TSH Receptor|{Teprotumumab} Protocol|{Teprotumumab} In Vitro|{Teprotumumab} manufacturer|{Teprotumumab} Cancer} 2.PMID:35116795 1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol|Smiles: OC(CCN1CCCCC1)(C1CC2CC1C=C2)C1C=CC=CC=1|InChiKey: YSXKPIUOCJLQIE-UHFFFAOYSA-N|InChi: InChI=1S/C21H29NO/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
