Product Name :
Fusapyrone
Description:
Fusapyrone, a broad-spectrum antifungal metabolite, is isolated from several Fusarium species. Structurally, fusapyrone consists of a 4-deoxy-β-xylo-hexopyranosyl C-glycosyl moiety bound to the C-6 of the 2-pyrone ring and a highly functionalized aliphatic chain. Fusapyrone exhibited low zoo-toxicity, as evidenced by a lack of toxicity against Artemia salina. Fusapyrone exerted considerable antifungal activity against several plant mycotoxigenic, pathogenic, and human pathogenic filamentous fungi, including Aspergillus flavus, Aspergillus niger, Aspergillus parasiticus, and Aspergillus fumigatus . Additionally, it had been investigated as a useful candidate for the control of postharvest crop diseases, including blocking the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes. However, fusapyrone was found to be ineffective toward yeasts isolated from fruits and plants and not toxic to Artemia salina (brine shrimp). The mechanism of action of fusapyrone is unknown and the structure of fusapyrone was revised in 2006. In vitro: Up to now, in vitro study of fusapyrone is still in the development stage. In vivo: Up to now, in vivo study of fusapyrone is still in the development stage.
CAS:
156856-31-4
Molecular Weight:
606.79
Formula:
C34H54O9
Chemical Name:
3-[(2S,3R,4S,6S)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-6-[(4E,6E)-8-[(1Z)-2,4-dimethyldec-1-en-1-yl]-3,9-dihydroxy-2,6-dimethylnona-4,6-dien-2-yl]-2-hydroxy-4H-pyran-4-one
Smiles :
CC(C/C(/C)=C\C(CO)/C=C(\C)/C=C/C(O)C(C)(C)C1=CC(=O)C([C@@H]2O[C@@H](C[C@H](O)[C@H]2O)CO)=C(O)O1)CCCCCC
InChiKey:
VMIZPSIJERGBNI-ZBNIOBMFSA-N
InChi :
InChI=1S/C34H54O9/c1-7-8-9-10-11-21(2)14-23(4)16-24(19-35)15-22(3)12-13-28(39)34(5,6)29-18-26(37)30(33(41)43-29)32-31(40)27(38)17-25(20-36)42-32/h12-13,15-16,18,21,24-25,27-28,31-32,35-36,38-41H,7-11,14,17,19-20H2,1-6H3/b13-12+,22-15+,23-16-/t21?,24?,25-,27-,28?,31+,32-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Fusapyrone, a broad-spectrum antifungal metabolite, is isolated from several Fusarium species. Structurally, fusapyrone consists of a 4-deoxy-β-xylo-hexopyranosyl C-glycosyl moiety bound to the C-6 of the 2-pyrone ring and a highly functionalized aliphatic chain. Fusapyrone exhibited low zoo-toxicity, as evidenced by a lack of toxicity against Artemia salina. Fusapyrone exerted considerable antifungal activity against several plant mycotoxigenic, pathogenic, and human pathogenic filamentous fungi, including Aspergillus flavus, Aspergillus niger, Aspergillus parasiticus, and Aspergillus fumigatus . Additionally, it had been investigated as a useful candidate for the control of postharvest crop diseases, including blocking the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes. However, fusapyrone was found to be ineffective toward yeasts isolated from fruits and plants and not toxic to Artemia salina (brine shrimp). The mechanism of action of fusapyrone is unknown and the structure of fusapyrone was revised in 2006.{{AB928} medchemexpress|{AB928} GPCR/G Protein|{AB928} Biological Activity|{AB928} In Vitro|{AB928} custom synthesis|{AB928} Epigenetic Reader Domain} In vitro: Up to now, in vitro study of fusapyrone is still in the development stage.{{Erlotinib} MedChemExpress|{Erlotinib} Autophagy|{Erlotinib} Biological Activity|{Erlotinib} Data Sheet|{Erlotinib} custom synthesis|{Erlotinib} Epigenetic Reader Domain} In vivo: Up to now, in vivo study of fusapyrone is still in the development stage.PMID:24670464 |Product information|CAS Number: 156856-31-4|Molecular Weight: 606.79|Formula: C34H54O9|Chemical Name: 3-[(2S,3R,4S,6S)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-6-[(4E,6E)-8-[(1Z)-2,4-dimethyldec-1-en-1-yl]-3,9-dihydroxy-2,6-dimethylnona-4,6-dien-2-yl]-2-hydroxy-4H-pyran-4-one|Smiles: CC(C/C(/C)=C\C(CO)/C=C(\C)/C=C/C(O)C(C)(C)C1=CC(=O)C([C@@H]2O[C@@H](C[C@H](O)[C@H]2O)CO)=C(O)O1)CCCCCC|InChiKey: VMIZPSIJERGBNI-ZBNIOBMFSA-N|InChi: InChI=1S/C34H54O9/c1-7-8-9-10-11-21(2)14-23(4)16-24(19-35)15-22(3)12-13-28(39)34(5,6)29-18-26(37)30(33(41)43-29)32-31(40)27(38)17-25(20-36)42-32/h12-13,15-16,18,21,24-25,27-28,31-32,35-36,38-41H,7-11,14,17,19-20H2,1-6H3/b13-12+,22-15+,23-16-/t21?,24?,25-,27-,28?,31+,32-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
