Product Name :
Guvacoline (hydrobromide)
Description:
Target: atrial and ileal muscarinic receptors IC50: 2.1 mM for growth inhibition of human buccal epithelial cells Guvacoline is a kind of natural alkaloid which is found in areca nuts that is related to the nootropic, arecoline. Guvacoline can function as a full agonist of atrial and ileal muscarinic receptors. In Vitro: In human buccal epithelial cells, Guvacoline could significantly decrease the colony-formation efficiency in a dose dependent manner, with the IC50 value of 2.1 mM. Besides, Guvacoline could also dose-dependently reduce the amount of total free low-molecular-weight thiols (0.88 mM Guvacoline caused 25% decrease) and increase the number of single strand breaks . In Vivo: No data available recently. Clinical trial: No data available recently.
CAS:
17210-51-4
Molecular Weight:
222.08
Formula:
C7H12BrNO2
Chemical Name:
methyl 1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide
Smiles :
Br.COC(=O)C1CNCCC=1
InChiKey:
DOXOETUWVNVADB-UHFFFAOYSA-N
InChi :
InChI=1S/C7H11NO2.BrH/c1-10-7(9)6-3-2-4-8-5-6;/h3,8H,2,4-5H2,1H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Lomitapide} web|{Lomitapide} Purity & Documentation|{Lomitapide} In Vitro|{Lomitapide} supplier|{Lomitapide} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Pralsetinib} medchemexpress|{Pralsetinib} RET|{Pralsetinib} Technical Information|{Pralsetinib} Description|{Pralsetinib} manufacturer|{Pralsetinib} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23916866
Additional information:
Target: atrial and ileal muscarinic receptors IC50: 2.1 mM for growth inhibition of human buccal epithelial cells Guvacoline is a kind of natural alkaloid which is found in areca nuts that is related to the nootropic, arecoline. Guvacoline can function as a full agonist of atrial and ileal muscarinic receptors. In Vitro: In human buccal epithelial cells, Guvacoline could significantly decrease the colony-formation efficiency in a dose dependent manner, with the IC50 value of 2.1 mM. Besides, Guvacoline could also dose-dependently reduce the amount of total free low-molecular-weight thiols (0.88 mM Guvacoline caused 25% decrease) and increase the number of single strand breaks . In Vivo: No data available recently. Clinical trial: No data available recently.|Product information|CAS Number: 17210-51-4|Molecular Weight: 222.08|Formula: C7H12BrNO2|Chemical Name: methyl 1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide|Smiles: Br.COC(=O)C1CNCCC=1|InChiKey: DOXOETUWVNVADB-UHFFFAOYSA-N|InChi: InChI=1S/C7H11NO2.BrH/c1-10-7(9)6-3-2-4-8-5-6;/h3,8H,2,4-5H2,1H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
