Product Name :
HS024
Description:
HS024 is a selective MC4 receptor antagonist, with Kis of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake.
CAS:
212370-59-7
Molecular Weight:
1268.52
Formula:
C58H81N19O10S2
Chemical Name:
(Z,2S)-N-[(1S)-4-carbamimidamido-1-[(Z)-[(1S)-1-[(Z)-[(1R)-1-[(Z)-[(1S)-4-carbamimidamido-1-[(Z)-[(1S)-1-[(Z)-[(Z)-[(1R)-1-(C-hydroxycarbonimidoyl)-2-sulfanylethyl]-C-hydroxycarbonimidoyl]methyl-C-hydroxycarbonimidoyl]-2-(1H-indol-3-yl)ethyl]-C-hydroxycarbonimidoyl]butyl]-C-hydroxycarbonimidoyl]-2-(naphthalen-2-yl)ethyl]-C-hydroxycarbonimidoyl]-2-(1H-imidazol-5-yl)ethyl]-C-hydroxycarbonimidoyl]butyl]-2-[(Z)-[(2R)-1-hydroxy-2-[(Z)-(1-hydroxyethylidene)amino]-3-sulfanylpropylidene]amino]hexanimidic acid
Smiles :
C/C(/O)=N/[C@@H](CS)/C(/O)=N/[C@@H](CCCC)/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CC1=CN=CN1)/C(/O)=N/[C@H](CC1=CC2=CC=CC=C2C=C1)/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CC1=CNC2=CC=CC=C12)/C(/O)=N/C/C(/O)=N/[C@@H](CS)C(=N)O
InChiKey:
GGQSIKFBYWFXSG-LQXMKOPKSA-N
InChi :
InChI=1S/C58H81N19O10S2/c1-3-4-14-40(74-56(87)47(30-89)70-32(2)78)51(82)72-41(16-9-20-65-57(60)61)53(84)77-45(25-37-27-64-31-69-37)55(86)75-43(23-33-18-19-34-11-5-6-12-35(34)22-33)54(85)73-42(17-10-21-66-58(62)63)52(83)76-44(24-36-26-67-39-15-8-7-13-38(36)39)50(81)68-28-48(79)71-46(29-88)49(59)80/h5-8,11-13,15,18-19,22,26-27,31,40-47,67,88-89H,3-4,9-10,14,16-17,20-21,23-25,28-30H2,1-2H3,(H2,59,80)(H,64,69)(H,68,81)(H,70,78)(H,71,79)(H,72,82)(H,73,85)(H,74,87)(H,75,86)(H,76,83)(H,77,84)(H4,60,61,65)(H4,62,63,66)/t40-,41-,42-,43+,44-,45-,46-,47-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
HS024 is a selective MC4 receptor antagonist, with Kis of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake.|Product information|CAS Number: 212370-59-7|Molecular Weight: 1268.52|Formula: C58H81N19O10S2|Chemical Name: (Z,2S)-N-[(1S)-4-carbamimidamido-1-[(Z)-[(1S)-1-[(Z)-[(1R)-1-[(Z)-[(1S)-4-carbamimidamido-1-[(Z)-[(1S)-1-[(Z)-[(Z)-[(1R)-1-(C-hydroxycarbonimidoyl)-2-sulfanylethyl]-C-hydroxycarbonimidoyl]methyl-C-hydroxycarbonimidoyl]-2-(1H-indol-3-yl)ethyl]-C-hydroxycarbonimidoyl]butyl]-C-hydroxycarbonimidoyl]-2-(naphthalen-2-yl)ethyl]-C-hydroxycarbonimidoyl]-2-(1H-imidazol-5-yl)ethyl]-C-hydroxycarbonimidoyl]butyl]-2-[(Z)-[(2R)-1-hydroxy-2-[(Z)-(1-hydroxyethylidene)amino]-3-sulfanylpropylidene]amino]hexanimidic acid|Smiles: C/C(/O)=N/[C@@H](CS)/C(/O)=N/[C@@H](CCCC)/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CC1=CN=CN1)/C(/O)=N/[C@H](CC1=CC2=CC=CC=C2C=C1)/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CC1=CNC2=CC=CC=C12)/C(/O)=N/C/C(/O)=N/[C@@H](CS)C(=N)O|InChiKey: GGQSIKFBYWFXSG-LQXMKOPKSA-N|InChi: InChI=1S/C58H81N19O10S2/c1-3-4-14-40(74-56(87)47(30-89)70-32(2)78)51(82)72-41(16-9-20-65-57(60)61)53(84)77-45(25-37-27-64-31-69-37)55(86)75-43(23-33-18-19-34-11-5-6-12-35(34)22-33)54(85)73-42(17-10-21-66-58(62)63)52(83)76-44(24-36-26-67-39-15-8-7-13-38(36)39)50(81)68-28-48(79)71-46(29-88)49(59)80/h5-8,11-13,15,18-19,22,26-27,31,40-47,67,88-89H,3-4,9-10,14,16-17,20-21,23-25,28-30H2,1-2H3,(H2,59,80)(H,64,69)(H,68,81)(H,70,78)(H,71,79)(H,72,82)(H,73,85)(H,74,87)(H,75,86)(H,76,83)(H,77,84)(H4,60,61,65)(H4,62,63,66)/t40-,41-,42-,43+,44-,45-,46-,47-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Flunarizine Purity |Shelf Life: ≥12 months if stored properly.Venetoclax Data Sheet |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33083892 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
