Product Name :
Lanicemine
Description:
Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.
CAS:
153322-05-5
Molecular Weight:
198.26
Formula:
C13H14N2
Chemical Name:
(1S)-1-phenyl-2-(pyridin-2-yl)ethan-1-amine
Smiles :
N[C@@H](CC1=CC=CC=N1)C1C=CC=CC=1
InChiKey:
FWUQWDCOOWEXRY-ZDUSSCGKSA-N
InChi :
InChI=1S/C13H14N2/c14-13(11-6-2-1-3-7-11)10-12-8-4-5-9-15-12/h1-9,13H,10,14H2/t13-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.|Product information|CAS Number: 153322-05-5|Molecular Weight: 198.26|Formula: C13H14N2|Chemical Name: (1S)-1-phenyl-2-(pyridin-2-yl)ethan-1-amine|Smiles: N[C@@H](CC1=CC=CC=N1)C1C=CC=CC=1|InChiKey: FWUQWDCOOWEXRY-ZDUSSCGKSA-N|InChi: InChI=1S/C13H14N2/c14-13(11-6-2-1-3-7-11)10-12-8-4-5-9-15-12/h1-9,13H,10,14H2/t13-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Renilla-Firefly Luciferase Dual Assay Kit web |Shelf Life: ≥12 months if stored properly.Tegaserod web |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:35092019 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Lanicemine produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects.Lanicemine (3, 10 or 30 mg/kg; intraperitoneal) not only engages brain circuits involved in the generation of gamma- electroencephalography (EEG), but also influences these networks independent of the broader systems-level disruptions typical of ketamine.|Products are for research use only. Not for human use.|
