Name :
Recombinant Cynomolgus IFN-alpha 13 Protein (hFc Tag)
Biological Activity :
Background :
Biological Activity :
Measured in antiviral assay using WISH human amnion cells infected with vesicular stomatitisvirus (VSV).The ED50 for this effect is typically 0.5-3 ng/mL.
Expression Host :
Cynomolgus
Source :
HEK293 Cells
Tag :
Protein Accession No. :
G7NFW4
NCBI Gene ID :
Synonyms :
Synonyms :
interferon, alpha 13
Amino Acid Sequence :
Molecular Weight :
The recombinant cynomolgus IFNA13 is a disulfide-linked homodimer. The reduced monomer comprises 407 amino acids and has a calculated molecular mass of 46.4 KDa.The apparent molecular mass of the protein is approximately 47 KDa respectively in SDS-PAGE.
Purity :
> 85 % as determined by SDS-PAGE
State of Matter :
Product Concentration :
Storage and Stability :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Endotoxin Level :
< 1.0 EU per μg of the protein as determined by the LAL method
Protein Construction :
A DNA sequence encoding the cynomolgus IFNA13 (G7NFW4) (Met1-Glu190) was expressed with the Fc region of human IgG1 at the C-terminus.
Buffer Solution :
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet.
Shipping :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Redissolution :
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Synonyms :
IFNA13 Protein, Cynomolgus IFN-alpha 13 背景信息
References & Citations :
Mahmutovic S, et al.. (2004) Significance of the interferon (IFN) in the therapy. Bosn J Basic Med Sci. 4(4): 42-4.Wang, et al.. (2004) Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2. J Neuroimmunol. 156(1-2): 107-12.
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