Ure 3. Concentrations of biochemical of lipid metabolism inside the serum of pigs exposed to low concentrations Figure three. Concentrations of biochemical parametersparameters of lipid metabolism inside the serum of pigs exof ZEN posed to(ZENlow; n = ten), high doses of ZEN(ZENlow;nn = ten), high doses10). All parameters are expressed inand low concentrations of ZEN (ZENhigh; = 10), and handle (n = of ZEN (ZENhigh; n = ten), millimoles per liter (mmol/L). High-density lipoprotein (HDL), low-density lipoprotein (LDL), and cholesterol (CHO) control are plotted around the left axis, whereas AZD4625 site absolutely free fatty acids (FFA) values are plottedliter (mmol/L). High-density lipo(n = 10). All parameters are expressed in millimoles per around the appropriate axis. The plot illustrates the values protein (HDL), low-density lipoprotein (LDL), and cholesterol (CHO) values are plotted around the left median (line within box); 25th and 75th percentiles (box); 1.5 instances the inter-quartile distance (Tukey; whiskers); and outliers axis, whereas free bar indicate the level ofvalues are of Kruskal allis test, whereas an asterisk over the whisker of ame(. Asterisks more than a fatty acids (FFA) significance plotted on the ideal axis. The plot illustrates the group indicates a substantial distinction of that group with (box); 1.5 occasions the inter-quartile distance 0.001; dian (line inside box); 25th and 75th percentilesthe handle group according to Dunn’s post-test. p (Tukey; p 0.01; p outliers (. Asterisks more than a bar indicate the level of significance of Kruskal allis whiskers); and0.05. test, whereas an asterisk more than the whisker of a group indicates a significant difference of that group 2.1.3. Glucose Metabolism with all the handle group according to to ZEN had a significant effect on biochemical parameters associated with glucose Exposure Dunn’s post-test. p 0.001; p 0.01; p 0.05.metabolism (Figure four). At day 7, substantial differences in glucose (p 0.001) have been observed. 2.1.3. Glucose Metabolism In comparison with manage, the glucose concentration was drastically larger in Pinacidil Potassium Channel ZENlow group when compared with controls (p 0.05), whereas it was drastically decrease in ZENhigh pigs Exposure to ZEN had a significanttime-point, substantially decrease levels of serum lactic acidglu(p 0.05). In the exact same impact on biochemical parameters associated with were observed in day 7, important variations in no variations were observed in cose metabolism (Figure four). AtZENlow pigs in comparison to manage, whereas glucose (p 0.001) were ZENhigh pigs. At day 21, variations in glucose were also significant (p 0.001). Compared observed. Comparedtoto handle, the glucose concentration was significantly and ZENhigh control, glucose concentrations have been drastically reduced in each ZENlow higher in ZENlow group in comparison to controlsturn, 0.05), whereas it was substantially lower in groups (p 0.05). In (p no variations in lactic acid concentrations were observed at 21 At of exposure time-point, substantially decrease levels of serum lactic ZENhigh pigs (p 0.05).days exactly the same to ZEN.acid have been observed in ZENlow pigs when compared with handle, whereas no differences were observed in ZENhigh pigs. At day 21, variations in glucose were also substantial (p 0.001). In comparison with manage, glucose concentrations have been significantly lower in both ZENlow and ZENhigh groups (p 0.05). In turn, no differences in lactic acid concentrations have been observed at 21 days of exposure to ZEN.R PEER Review 13, 790 Toxins 2021,five of 16 5 ofFigure four. Concentrations of biochem.
