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With continuous developments inside the pig business, early weaning of piglets has come to be a general HSF1 Molecular Weight consensus (1); the period is usually accompanied by diarrhea, which brings massive financial losses to the pig market (two). During weaning, piglets are exposed to and should speedily adapt to various psychological, environmental, and physiological stressors (1), all of which are associated with weaningrelated anxiety, which results in modifications in intestinal structure and function at the same time as imbalances in intestinal microbiota (3), sooner or later leading to post-weaning stress diarrhea. At present, dietary intervention may be the most common approach to alleviate weaning anxiety diarrhea (4, five), and plant extracts can strengthen the growth overall performance, antioxidant capacity, and immunity of livestock and poultry to prevent a variety of diseases (six, 7). Prior research in our laboratory have shown that Plantago asiatica L. (CQC), an important medicinal plant, can successfully treat diarrhea (eight). Around the basis on the previous research results, two kinds of traditional Chinese medicine (TCM), Astragalus propinquus Schischkin (HQ),

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